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E0771 Breast Adenocarcinoma Cell Line
Price range: $561.00 through $1,071.64
Useful for cancer research in vitro and in animal transplantation xenografts. E0771 cells are especially useful in experimental studies of metastasis and mechanisms of immune system evasion. E0771 cells injected into host mice reproducibly form tumors that can be used as allograft models of adenocarcinoma and for new drug testing.
E0771 murine breast cancer cell line adenocarcinoma cell line originally isolated as a spontaneous tumor from C57BL/6 mouse (Sugiura, K and Stock, C.C., 1952) and adapted for anti‐cancer drug testing by Sirotnak et al., 1984
- Metastasis: E0771 cells are an important biological tool to help understand how cancer forms and spreads throughout the body.
- Allograft/Xenograft Transplanting: E0771 cells into healthy mice reproducibly forms solid tumors for research purposes.
- Adenocarcinoma: This type of cancer affects the endocrine system organs.
- Immune System Evasion: This is the primary mechanism through which E0771 cells are capable of forming tumors and migrating efficiently throughout the body.
E0771 cells are, thus, an excellent research tool for screening NCEs, lead compounds and early drug development pipelines.
New Premium Package! includes STR Authentication/Pathogen Tested
E0771 Cell Line – Murine Breast Cancer Cell Line
Product: #94A001
Overview
Medullary breast adenocarcinoma cell line originally isolated as a spontaneous tumor from C57BL/6 mouse (Sugiura, K and Stock, C.C., 1952) and adapted for anti‐cancer drug testing by Sirotnak et al., 1984 ( https://www.ncbi.nlm.nih.gov/pubmed/6690070 ). Cell culture conditions as described by Ewens et al., 2005 (https://www.ncbi.nlm.nih.gov/pubmed/16312045) allow maintenance as a cell monolayer.
Purification
N/A
Formulation
10 to 20 X 10^6 cells provided in tissue culture flask or as a frozen cell pellet in cryoprotectant.
Product Usage
Cell culture. RPMI 1640 medium supplemented with 10 mmol/L HEPES and 5% to 10% Fetal Bovine Serum. Use of antibiotics, such as penicillin (100 units/ml) and streptomycin (100 μg/ml) is not required. The decision to use antibiotics is left to the discretion of the investigator.
Testing
Cultured on tissue culture plastic in 5% fetal bovine serum with either DMEM or RPMI 1640.
New Premium Package!
Selected Lots of the E0771 cell line are authenticated by short tandem repeat profiling and screened for the following pathogens:
Pathogen Testing of CH3 Biosystems Breast Cancer Cell Line
(M. spp., M. pulmonis) – Mycoplasma
(TMEV) – Theiler’s Murine Encephalomyelitis Virus
(PVM) – Pneumonia Virus of Mice
(MVM) – Minute Virus of Mice
(MHV) – Mouse Hepatitis Virus
(MPV1-5) – Mouse Parvovirus
(C. bovis) – Corynebacterium bovis, Sendai Virus
In addition, species-specific PCR evaluation is performed to rule out any contamination by rat, human, hamster or monkey cells.
Screening for additional pathogens may be available upon request. Contact us for customized pricing.
Storage
Place in culture immediately upon arrival; 37° humidified (100%) CO2 incubator. Use 5% CO2.
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| Dimensions | N/A |
| Premium Package | Tested, Regular |
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