Histone methylation modifiers in cellular signaling pathways

Histone methylation modifiers in cellular signaling pathways Histone methyltransferases and demethylases epigenetically regulate gene expression by modifying histone methylation status in numerous cellular processes, including cell differentiation and proliferation. These modifiers also control methylation levels...

Methylated CREB binding protein is nuclear – Sept 2015

Methylated CREB binding protein is nuclear Proper embryonic development requires a fine-tuned control of gene expression, which is achieved in part through the activity of transcription coactivators or corepressors. The nuclear coactivator cAMP-response element-binding protein (CREB) binding protein (CREBBP or CBP) interacts with numerous transcription factors...