Product Spotlight – Trademark

 CH3 BIOSYSTEMS®   On March 20, 2018 CH3 BIOSYSTEMS became a registered trademark for the protection of the unique R&D products produced in Buffalo, New York and sold to customers all over the world....

Research Review Series (2 of 3)

THE INTERSECTION OF CANCER AND PROTEIN METHYLATION   William Pratt, CH3 Biosystems Lab Intern Introduction   Protein arginine methyltransferases (PRMTs) are transcriptional coactivators, a type of coregulator that affects a transcription factor to increase the rate of transcription of a gene by recruiting general transcription machinery to the promoter region....

Research Review Series (1 of 3)

PRMT5 and Cancer  William Pratt, CH3 Biosystems Lab Intern   Protein methylation is a common post translational modification that has grown in importance as a research topic in recent years. The role of protein methylation in cancer is extremely complicated and thus very difficult to discuss broadly. This...

Product Spotlight

PC12 Pheochromocytoma Cells     Advantage of PC12 Cells Every year thousands of people in the world are diagnosed with neurodevelopmental diseases and cancer. The need for better and more effective medications that can be brought to the market faster is on the rise. Each new drug is created...

Research Spotlight

Methyltransferase Inhibitors Recent exciting news in the field of personalized medicine of cancer patients: new developments on the collaboration between Epizyme and GlaxoSmithKline may contribute the advancement of cancer treatment research tremendously.  Additionally, there has been new progress made by CH3 BioSystems to create a new...

Product Spotlight

Cell Lines Cell lines are derived from normal or diseased tissue that is disaggregated and subjected to limited dilution to generate one or a few cells. Therefore, after several dozen rounds of division, cultures of cell line consist of cells with uniform genetic make-up and additionally homogenous biochemical...

Expression Vector

Tumors, p53 and survivin

A recent New York Times article published on December 22, 2012 described efforts to develop new drug compounds capable of targeting cancer cells that arise in many different organs of the human body.  Unfortunately, much was left unsaid with little source information to track down more specifics.  Fierce...