CH3 BIOSYSTEMS® On March 20, 2018 CH3 BIOSYSTEMS became a registered trademark for the protection of the unique R&D products produced in Buffalo, New York and sold to customers all over the world.
THE INTERSECTION OF CANCER AND PROTEIN METHYLATION William Pratt, CH3 Biosystems Lab Intern Introduction Protein arginine methyltransferases (PRMTs) are transcriptional coactivators, a type of coregulator that affects a transcription factor to increase the rate of transcription of a gene by recruiting general transcription machinery to the promoter region. The aberrant expression of PRMTs … Read more
PRMT5 and Cancer William Pratt, CH3 Biosystems Lab Intern Protein methylation is a common post translational modification that has grown in importance as a research topic in recent years. The role of protein methylation in cancer is extremely complicated and thus very difficult to discuss broadly. This series of posts focuses on the relationship … Read more
PC12 Pheochromocytoma Cells Advantage of PC12 Cells Every year thousands of people in the world are diagnosed with neurodevelopmental diseases and cancer. The need for better and more effective medications that can be brought to the market faster is on the rise. Each new drug is created from years of research and experiments … Read more
Methyltransferase Inhibitors Recent exciting news in the field of personalized medicine of cancer patients: new developments on the collaboration between Epizyme and GlaxoSmithKline may contribute the advancement of cancer treatment research tremendously. Additionally, there has been new progress made by CH3 BioSystems to create a new drug discovery platform. New development on the collaboration between … Read more
Cell Lines Cell lines are derived from normal or diseased tissue that is disaggregated and subjected to limited dilution to generate one or a few cells. Therefore, after several dozen rounds of division, cultures of cell line consist of cells with uniform genetic make-up and additionally homogenous biochemical composition. Here at CH3 BioSystems, our cell lines are … Read more
A recent New York Times article published on December 22, 2012 described efforts to develop new drug compounds capable of targeting cancer cells that arise in many different organs of the human body. Unfortunately, much was left unsaid with little source information to track down more specifics. Fierce Biotech regurgitated the essentials of the article, but little in the way of … Read more